{"id":1069,"date":"2020-06-17T17:13:40","date_gmt":"2020-06-17T15:13:40","guid":{"rendered":"https:\/\/www.inositoli.it\/home\/"},"modified":"2020-09-01T15:50:38","modified_gmt":"2020-09-01T13:50:38","slug":"home","status":"publish","type":"page","link":"https:\/\/www.inositoli.com\/en\/","title":{"rendered":"Home"},"content":{"rendered":"

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Inositols: everything you need to know on myo-inositol and d-chiro-inositol<\/h1>\n

[\/et_pb_slide][\/et_pb_fullwidth_slider][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.3.1″ background_color=”#e7e7e8″][et_pb_row column_structure=”3_4,1_4″ _builder_version=”4.3.1″][et_pb_column type=”3_4″ _builder_version=”4.3.1″][et_pb_text _builder_version=”4.3.3″ header_2_font_size=”40px” header_2_font_size_tablet=”35px” header_2_font_size_phone=”28px” header_2_font_size_last_edited=”on|phone”]<\/p>\n

What is inositol<\/h2>\n

Inositol is a natural molecule<\/strong> that is found in the phospholipids of cell membranes, in the lipoproteins of the plasma and, in the form of inositol-phosphates, in the nucleus of cells.<\/p>\n

When we speak of inositol, we are actually talking about \u00a0a group of nine differents stereoisomers, <\/strong>so it would be more correct to use the plural “Inositols”.<\/strong> Among these, however, the term inositol is generally used to refer to the most bioavailable type, myo-inositol.<\/strong>[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.3.1″][et_pb_image src=”http:\/\/inositoli.it\/wp-content\/uploads\/2020\/02\/inositolo-trasp.png” _builder_version=”4.3.1″][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.3.1″ background_enable_color=”off”][et_pb_row _builder_version=”4.3.1″][et_pb_column type=”4_4″ _builder_version=”4.3.1″][et_pb_text _builder_version=”4.3.3″ header_2_font_size=”40px” header_2_font_size_tablet=”35px” header_2_font_size_phone=”28px” header_2_font_size_last_edited=”on|phone”]<\/p>\n

Where to find it in nature<\/h2>\n

Inositol is widespread in vegetables<\/strong>: green beans, peas, asparagus and carrots are rich in it.<\/p>\n

It is also found inside fruits, like pears, cherries, apples and tomatoes. Inositol is present in oats, corn and cereals as a component of lecithins<\/strong>. In animal tissues<\/strong>, myo-inositol is mainly present in free form or as phosphatidylinositol (PI). Tissues as brain and muscles, are full of it. Huge amounts of myo-inositol can be present in the sperm, oocyte and embryo during the early stages of embryonic development.[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.3.3″ background_color=”#007b6e”][et_pb_row _builder_version=”4.3.1″][et_pb_column type=”4_4″ _builder_version=”4.3.1″][et_pb_text _builder_version=”4.3.3″ header_2_font_size=”40px” background_layout=”dark” header_2_font_size_tablet=”35px” header_2_font_size_phone=”28px” header_2_font_size_last_edited=”on|phone”]<\/p>\n

What are the benefits<\/h2>\n

Today, myo-inositol<\/strong> represent a safe and effective therapy<\/strong> applied in several disease and pathologies.<\/p>\n

In PCOS, the administration of myo-inositol caused the remission of symptoms and the reduction of male hormone secretion; In case of male infertility<\/strong>, inositol has improved, according to reports from various studies, motility and sperm count<\/strong>, while in women it improves the oocyte and embryonic quality.<\/strong><\/p>\n

Furthermore, myo-inositol produces an increase in the sensitivity of the serotonin receptor, also known as the happy hormone, with benefits on anxiety disorders.<\/strong><\/p>\n

The benefits of inositol have also been investigated in relation to diabetes<\/strong> and the prevention and treatment of metabolic syndrome.<\/strong>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.3.1″][et_pb_row _builder_version=”4.3.1″][et_pb_column type=”4_4″ _builder_version=”4.3.1″][et_pb_text _builder_version=”4.3.3″ header_2_font_size=”40px” custom_margin=”||-2px|||” header_2_font_size_tablet=”35px” header_2_font_size_phone=”28px” header_2_font_size_last_edited=”on|phone”]<\/p>\n

But what difference is there between Myo<\/span> and D-chiro-inositol<\/span>?<\/h2>\n

[\/et_pb_text][et_pb_text _builder_version=”4.3.3″]Close to Myo-inositol<\/strong> we can also find D-chiro-inositol<\/strong>. Both of them, in the form of inositolophosphoglycans, are “second messengers” of the insulin hormone.<\/p>\n

However, even if their biological functions are often confused, it should be remembered that myo and d-chiro have different roles within the body<\/strong>.[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ use_custom_gutter=”on” gutter_width=”4″ _builder_version=”4.3.3″][et_pb_column type=”1_2″ _builder_version=”4.3.1″][et_pb_text _builder_version=”4.3.3″]<\/p>\n

Myo-inositol<\/span><\/h2>\n

is involved in the use of transporters
\nand in the glucose\u2019s cellular absorption<\/strong><\/p>\n

[\/et_pb_text][et_pb_image src=”http:\/\/inositoli.it\/wp-content\/uploads\/2020\/02\/Untitled-2_0001_Vector-Smart-Object.jpg” _builder_version=”4.3.3″ max_width=”400px” module_alignment=”center”][\/et_pb_image][et_pb_text _builder_version=”4.3.3″]Myo is synthesized endogenously from glucose 6-phosphate and incorporated into cell membrane as phosphatidylinositol phosphate. In addition, it is converted into D-chiro-inositol by an enzyme, epimerase, which is insulin dependent.<\/p>\n

Myo regulates the activity of several hormones such as insulin, thyroid hormone (TSH) and follicle stimulating hormone (FSH).<\/strong>[\/et_pb_text][et_pb_button button_url=”http:\/\/inositoli.it\/en\/myo-inositol\/” button_text=”go to the article” button_alignment_tablet=”” button_alignment_phone=”center” button_alignment_last_edited=”on|phone” _builder_version=”4.4.2″ custom_button=”on” button_text_color=”#489bd6″ button_border_color=”#489bd6″ button_border_radius=”100px” button_font=”|700|||||||”][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.3.1″][et_pb_text _builder_version=”4.3.3″]<\/p>\n

D-chiro-inositol<\/span><\/h2>\n

it is involved<\/strong> in glucose metabolism<\/strong>
\nand storage <\/strong>in the form of glycogen<\/strong>.<\/p>\n

[\/et_pb_text][et_pb_image src=”http:\/\/inositoli.it\/wp-content\/uploads\/2020\/02\/Untitled-2_0000_Vector-Smart-Object.jpg” align=”center” _builder_version=”4.3.3″ max_width=”400px”][\/et_pb_image][et_pb_text _builder_version=”4.3.3″]Overall, D-chiro-inositol is less abundant in nature than myo-inositol.\u00a0It can be found in high concentrations into the tissues that store glycogen and who need to conserve energy: Basically adipose tissue and liver!\u00a0<\/span><\/p>\n

D-chiro is involved in the synthesis of insulin-dependent androgens and acts as modulator of aromatase.<\/strong>[\/et_pb_text][et_pb_button button_url=”http:\/\/inositoli.it\/en\/d-chiro\/” button_text=”go to the article” button_alignment_tablet=”” button_alignment_phone=”center” button_alignment_last_edited=”on|phone” _builder_version=”4.4.2″ custom_button=”on” button_text_color=”#fab517″ button_border_color=”#fab517″ button_border_radius=”100px” button_font=”|700|||||||”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.3.3″ background_color=”#266194″ custom_padding=”0px||0px|||”][et_pb_row _builder_version=”4.3.1″ custom_padding=”||0px|||”][et_pb_column type=”4_4″ _builder_version=”4.3.1″][et_pb_text _builder_version=”4.3.3″ header_2_font_size=”40px” background_layout=”dark” header_2_font_size_tablet=”35px” header_2_font_size_phone=”28px” header_2_font_size_last_edited=”on|phone”]<\/p>\n

Myo and D-chiro 40:1
\nA question of science!<\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.3.1″][et_pb_row _builder_version=”4.3.1″][et_pb_column type=”4_4″ _builder_version=”4.3.1″][et_pb_text _builder_version=”4.3.3″]Among the questions that most affect scientific debate on the inositols certainly there is the one related to: “Myo-inositol, D-chiro-inositol or both for PCOS?”. It is necessary that the answer to this question comes from science and clinical evidence.[\/et_pb_text][et_pb_text _builder_version=”4.4.2″ text_font=”|700|||||||” text_font_size=”24px”]Scientific studies have shown the benefits of the combined 40:1<\/span>formulation of MYO and DCI su:[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”3_5,2_5″ custom_padding_last_edited=”on|tablet” _builder_version=”4.3.3″ custom_padding=”0px||20px||false|false” custom_padding_tablet=”||0px||false|false” custom_padding_phone=””][et_pb_column type=”3_5″ _builder_version=”4.3.1″][et_pb_text module_class=”c-pika c-pika–1″ _builder_version=”4.4.2″ text_font=”|700|||||||” text_text_color=”#af1551″ text_font_size=”24px” text_line_height=”1em” background_color=”#E9E9E9″ custom_padding=”16px||10px|20px|false|false” link_option_url=”https:\/\/www.europeanreview.org\/?s=The+combined+therapy+with+myo-inositol+and+D-chiro-inositol+reduces+the+risk+of+metabolic+disease+in+PCOS+overweight+patients+compared+to+myo-inositol+supplementation+alone” link_option_url_new_window=”on”]PCOS[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.3.1″][et_pb_button button_url=”https:\/\/www.europeanreview.org\/?s=The+combined+therapy+with+myo-inositol+and+D-chiro-inositol+reduces+the+risk+of+metabolic+disease+in+PCOS+overweight+patients+compared+to+myo-inositol+supplementation+alone” url_new_window=”on” button_text=”Read the article” disabled_on=”on|on|off” _builder_version=”4.4.2″ custom_button=”on” button_text_color=”#af1551″ button_border_color=”#af1551″ button_border_radius=”100px” button_font=”|700|||||||” custom_margin=”5px||||false|false”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”3_5,2_5″ custom_padding_last_edited=”on|tablet” _builder_version=”4.3.3″ custom_padding=”0px||20px||false|false” custom_padding_tablet=”||0px||false|false” custom_padding_phone=””][et_pb_column type=”3_5″ _builder_version=”4.3.1″][et_pb_text module_class=”c-pika c-pika–2″ _builder_version=”4.4.2″ text_font=”|700|||||||” text_text_color=”#e04c12″ text_font_size=”24px” text_line_height=”1em” background_color=”#E9E9E9″ custom_padding=”16px||10px|20px|false|false” link_option_url=”https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5078644\/” link_option_url_new_window=”on”]Metabolism and obesity[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.3.1″][et_pb_button button_url=”https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5078644\/” url_new_window=”on” button_text=”Read the article” disabled_on=”on|on|off” _builder_version=”4.4.2″ custom_button=”on” button_text_color=”#e04c12″ button_border_color=”#e04c12″ button_border_radius=”100px” button_font=”|700|||||||” custom_margin=”5px||||false|false”][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”3_5,2_5″ custom_padding_last_edited=”on|tablet” _builder_version=”4.3.3″ custom_padding=”0px||20px||false|false” custom_padding_tablet=”||0px||false|false” custom_padding_phone=””][et_pb_column type=”3_5″ _builder_version=”4.3.1″][et_pb_text module_class=”c-pika c-pika–3″ _builder_version=”4.4.2″ text_font=”|700|||||||” text_font_size=”24px” text_line_height=”1em” background_color=”#E9E9E9″ custom_padding=”16px||10px|20px|false|false” link_option_url=”https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4989075\/” link_option_url_new_window=”on”]Infertility and oocite quality[\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”4.3.1″][et_pb_button button_url=”https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4989075\/” url_new_window=”on” button_text=”Read the article” disabled_on=”on|on|off” _builder_version=”4.4.2″ custom_button=”on” button_text_color=”#000000″ button_border_color=”#000000″ button_border_radius=”100px” button_font=”|700|||||||” custom_margin=”5px||||false|false”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.4.2″ background_color=”#0d7d70″ custom_padding=”0px||1px|||”][et_pb_row _builder_version=”4.3.1″ custom_padding=”36px||0px|||”][et_pb_column type=”4_4″ _builder_version=”4.3.1″][et_pb_text _builder_version=”4.3.3″ header_2_font_size=”40px” background_layout=”dark” header_2_font_size_tablet=”35px” header_2_font_size_phone=”28px” header_2_font_size_last_edited=”on|phone”]<\/p>\n

Learn More<\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.3.1″][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”4.3.1″][et_pb_column type=”1_3″ _builder_version=”4.3.1″][et_pb_text module_class=”c-home-explore c-home-explore–1″ _builder_version=”4.4.2″ text_font=”|700|||||||” text_text_color=”#489bd6″ text_font_size=”34px” background_color=”#ebf5fb” custom_padding=”40px||40px||false|false” link_option_url=”http:\/\/inositoli.it\/en\/myo-inositol\/”]<\/p>\n

Myo-inositol<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.3.1″][et_pb_text module_class=”c-home-explore c-home-explore–2″ _builder_version=”4.4.2″ text_font=”|700|||||||” text_text_color=”#fab517″ text_font_size=”34px” background_color=”#fff7ea” custom_padding=”40px||40px||false|false” link_option_url=”http:\/\/inositoli.it\/en\/d-chiro\/”]<\/p>\n

D-chiro-inositol<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.3.1″][et_pb_text module_class=”c-home-explore c-home-explore–3″ _builder_version=”4.4.8″ text_font=”|700|||||||” text_text_color=”#266194″ text_font_size=”34px” background_color=”#e9f0f4″ custom_padding=”40px||40px||false|false” link_option_url=”http:\/\/inositoli.it\/en\/myo-d-chiro-401\/” hover_enabled=”0″]<\/p>\n

40:1<\/p>\n

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Alpha-lactalbumin<\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.3.1″][et_pb_text module_class=”c-home-explore c-home-explore–5″ _builder_version=”4.4.8″ text_font=”|700|||||||” text_text_color=”#af1551″ text_font_size=”34px” background_color=”#f6e8ee” custom_padding=”40px||40px||false|false” link_option_url=”http:\/\/inositoli.it\/en\/pcos\/” hover_enabled=”0″]<\/p>\n

PCOS<\/p>\n

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Overweight<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

Inositols: everything you need to know on myo-inositol and d-chiro-inositolWhat is inositol Inositol is a natural molecule that is found in the phospholipids of cell membranes, in the lipoproteins of the plasma and, in the form of inositol-phosphates, in the nucleus of cells. When we speak of inositol, we are actually talking about \u00a0a group […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-1069","page","type-page","status-publish","hentry"],"yoast_head":"\nInositols: everything you need to know on myo-inositol and d-chiro-inositol - Inositoli<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.inositoli.com\/en\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Inositols: everything you need to know on myo-inositol and d-chiro-inositol - Inositoli\" \/>\n<meta property=\"og:description\" content=\"Inositols: everything you need to know on myo-inositol and d-chiro-inositolWhat is inositol Inositol is a natural molecule that is found in the phospholipids of cell membranes, in the lipoproteins of the plasma and, in the form of inositol-phosphates, in the nucleus of cells. 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